SN Tributyrin

Tributyrin

SN Tributyrin is based on tributyrin, a neutral and chemically stable ester composed of butyric acid and glycerol. Tributyrin is rapidly hydrolyzed by pancreatic and gastric lipases to glycerol and 3 butyrate molecules in the proximal intestinal tract. Experimental studies show an intact tight junction protein network in the ileum, proximal colon and jejunum; a sign of a healthy intestinal morphology. Since antibiotic usage can cause profound changes in gut microbiota, it is likely that there is a consequential reduction of butyrate produced in the GI tract; for this reason the administration of tributyrin serves as primary energy source, promotes growth of epithelial cells and trans-epithelial resistance and consequently reduced permeability. In general, tributyrin has positive effects on the reformation of epithelial cells and controlling the immune response through the regulation and the expression of anti-inflammatory cytokines.

Unique mode of action

SN Tributyrin shows a particular chemical behavior; it is hydro-dispersible and as a self-emulsifying compound. Its chemical characteristics allow these molecules to be active in four different environments: water, feed, stomach and intestinal tract. The fact that these molecules are hydro- and lipophilic can be considered as an advantage.

Advantages

  • Antibacterial
  • Unique mode of action
  • Heat stable
  • Non-corrosive
  • Neutral smell & taste

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